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DNA priming and gp120 boosting induces HIV-specific antibodies in a randomized clinical trial

DNA priming and gp120 boosting induces HIV-specific antibodies in a randomized clinical trial

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6819112

DNA priming and gp120 boosting induces HIV-specific antibodies in a randomized clinical trial

About this item

Full title

DNA priming and gp120 boosting induces HIV-specific antibodies in a randomized clinical trial

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2019-11, Vol.129 (11), p.4769-4785

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

BACKGROUNDRV144 is the only preventive HIV vaccine regimen demonstrating efficacy in humans. Attempting to build upon RV144 immune responses, we conducted a phase 1, multicenter, randomized, double-blind trial to assess the safety and immunogenicity of regimens substituting the DNA-HIV-PT123 (DNA) vaccine for ALVAC-HIV in different sequences or com...

Alternative Titles

Full title

DNA priming and gp120 boosting induces HIV-specific antibodies in a randomized clinical trial

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6819112

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6819112

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI128699

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