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Nuclear envelope-localized torsinA-LAP1 complex regulates hepatic VLDL secretion and steatosis

Nuclear envelope-localized torsinA-LAP1 complex regulates hepatic VLDL secretion and steatosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6819140

Nuclear envelope-localized torsinA-LAP1 complex regulates hepatic VLDL secretion and steatosis

About this item

Full title

Nuclear envelope-localized torsinA-LAP1 complex regulates hepatic VLDL secretion and steatosis

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2019-11, Vol.129 (11), p.4885-4900

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Deciphering novel pathways regulating liver lipid content has profound implications for understanding the pathophysiology of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. Recent evidence suggests that the nuclear envelope is a site of regulation of lipid metabolism but there is limited appreciation of the responsible mechanisms...

Alternative Titles

Full title

Nuclear envelope-localized torsinA-LAP1 complex regulates hepatic VLDL secretion and steatosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6819140

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6819140

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI129769

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