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Removal of DNA-fragmented spermatozoa using flow cytometry and sorting does not improve the outcome...

Removal of DNA-fragmented spermatozoa using flow cytometry and sorting does not improve the outcome...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6823333

Removal of DNA-fragmented spermatozoa using flow cytometry and sorting does not improve the outcome of intracytoplasmic sperm injection

About this item

Full title

Removal of DNA-fragmented spermatozoa using flow cytometry and sorting does not improve the outcome of intracytoplasmic sperm injection

Publisher

New York: Springer US

Journal title

Journal of assisted reproduction and genetics, 2019-10, Vol.36 (10), p.2079-2086

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Purpose
The DNA fragmentation in sperm is associated with reduced outcome in assisted reproduction. Using YoPro1 as the staining dye and flow cytometry and sorting (FACS), the number of spermatozoa with DNA fragmentation can be lowered to 5%. Can the cumulative outcome of ICSI be improved using FACS?
Methods
A prospective, randomized, doub...

Alternative Titles

Full title

Removal of DNA-fragmented spermatozoa using flow cytometry and sorting does not improve the outcome of intracytoplasmic sperm injection

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6823333

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6823333

Other Identifiers

ISSN

1058-0468,1573-7330

E-ISSN

1573-7330

DOI

10.1007/s10815-019-01571-1

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