Increased levels of superoxide dismutase suppress meiotic segregation errors in aging oocytes
Increased levels of superoxide dismutase suppress meiotic segregation errors in aging oocytes
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Language
English
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Contents
The risk of meiotic segregation errors increases dramatically during a woman’s thirties, a phenomenon known as the maternal age effect. In addition, several lines of evidence indicate that meiotic cohesion deteriorates as oocytes age. One mechanism that may contribute to age-induced loss of cohesion is oxidative damage. In support of this model, we...
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Full title
Increased levels of superoxide dismutase suppress meiotic segregation errors in aging oocytes
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6823651
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6823651
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ISSN
0009-5915
E-ISSN
1432-0886
DOI
10.1007/s00412-019-00702-y