Pain Inhibits GRPR Neurons via GABAergic Signaling in the Spinal Cord
Pain Inhibits GRPR Neurons via GABAergic Signaling in the Spinal Cord
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
It has been known that algogens and cooling could inhibit itch sensation; however, the underlying molecular and neural mechanisms remain poorly understood. Here, we show that the spinal neurons expressing gastrin releasing peptide receptor (GRPR) primarily comprise excitatory interneurons that receive direct and indirect inputs from C and Aδ fibers...
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Full title
Pain Inhibits GRPR Neurons via GABAergic Signaling in the Spinal Cord
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6825123
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6825123
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-52316-0
