Structural Features of a Conformation-dependent Antigen Epitope on ORFV-B2L Recognized by the 2E4 mA...
Structural Features of a Conformation-dependent Antigen Epitope on ORFV-B2L Recognized by the 2E4 mAb
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Author / Creator
Yu, Yongzhong , Zhao, Wenbo , Tan, Qiang , Zhang, Xue , Wang, Mengyao , Duan, Xuyang , Liu, Yuanyuan , Wu, Zhijun , Ma, Jinzhu , Song, Baifen , Zhao, Rui , Zhao, Kui , Lian, Zhengxing and Cui, Yudong
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Previously, we successfully prepared a monoclonal antibody (mAb) named 2E4, that directly recognizes the major envelope protein B2L of the orf virus (ORFV), but there is little information about its epitope. Here, we meticulously mapped the 2E4 epitope through combinatorial programs and identified the functional binding domain and a key amino acid...
Alternative Titles
Full title
Structural Features of a Conformation-dependent Antigen Epitope on ORFV-B2L Recognized by the 2E4 mAb
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6834619
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6834619
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-52446-5
