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Repression of eEF2K transcription by NF-κB tunes translation elongation to inflammation and dsDNA-se...

Repression of eEF2K transcription by NF-κB tunes translation elongation to inflammation and dsDNA-se...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6842605

Repression of eEF2K transcription by NF-κB tunes translation elongation to inflammation and dsDNA-sensing

About this item

Full title

Repression of eEF2K transcription by NF-κB tunes translation elongation to inflammation and dsDNA-sensing

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2019-11, Vol.116 (45), p.22583-22590

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Gene expression is rapidly remodeled by infection and inflammation in part via transcription factor NF-κB activation and regulated protein synthesis. While protein synthesis is largely controlled by mRNA translation initiation, whether cellular translation elongation factors are responsive to inflammation and infection remains poorly understood. He...

Alternative Titles

Full title

Repression of eEF2K transcription by NF-κB tunes translation elongation to inflammation and dsDNA-sensing

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6842605

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6842605

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1909143116

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