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Uncovering the Genomic Landscape in Newly Diagnosed and Relapsed Pediatric Cytogenetically Normal FL...

Uncovering the Genomic Landscape in Newly Diagnosed and Relapsed Pediatric Cytogenetically Normal FL...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6853146

Uncovering the Genomic Landscape in Newly Diagnosed and Relapsed Pediatric Cytogenetically Normal FLT 3‐ ITD AML

About this item

Full title

Uncovering the Genomic Landscape in Newly Diagnosed and Relapsed Pediatric Cytogenetically Normal FLT 3‐ ITD AML

Publisher

Hoboken: John Wiley & Sons, Inc

Journal title

Clinical and translational science, 2019-11, Vol.12 (6), p.641-647

Language

English

Formats

Publication information

Publisher

Hoboken: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Fms‐like tyrosine kinase 3 (
FLT
3
) internal tandem duplication (
ITD
) mutations, common in pediatric acute myeloid leukemia (
AML
), associate with early relapse and poor prognosis. Past studies have suggested additional cooperative mutations are required for leukemogenesis in
FLT
3

ITD
+
AML
. Using

Alternative Titles

Full title

Uncovering the Genomic Landscape in Newly Diagnosed and Relapsed Pediatric Cytogenetically Normal FLT 3‐ ITD AML

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6853146

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6853146

Other Identifiers

ISSN

1752-8054

E-ISSN

1752-8062

DOI

10.1111/cts.12669

How to access this item