Decrease in p3-Alcβ37 and p3-Alcβ40, products of Alcadein β generated by γ-secretase cleavages, in a...
Decrease in p3-Alcβ37 and p3-Alcβ40, products of Alcadein β generated by γ-secretase cleavages, in aged monkeys and patients with Alzheimer's disease
About this item
Full title
Author / Creator
Hata, Saori , Omori, Chiori , Kimura, Ayano , Saito, Haruka , Kimura, Nobuyuki , Gupta, Veer , Pedrini, Steve , Hone, Eugene , Chatterjee, Pratishtha , Taddei, Kevin , Kasuga, Kensaku , Ikeuchi, Takeshi , Waragai, Masaaki , Nishimura, Masaki , Hu, Anqi , Nakaya, Tadashi , Meijer, Laurent , Maeda, Masahiro , Yamamoto, Tohru , Masters, Colin L. , Rowe, Chris C. , Ames, David , Yamamoto, Kazuo , Martins, Ralph N. , Gandy, Sam and Suzuki, Toshiharu
Publisher
United States: Elsevier Inc
Journal title
Language
English
Formats
Publication information
Publisher
United States: Elsevier Inc
Subjects
More information
Scope and Contents
Contents
Neuronal p3-Alcβ peptides are generated from the precursor protein Alcadein β (Alcβ) through cleavage by α- and γ-secretases of the amyloid β (Aβ) protein precursor (APP). To reveal whether p3-Alcβ is involved in Alzheimer's disease (AD) contributes for the development of novel therapy and/or drug targets.
We developed new sandwich enzyme-linked...
Alternative Titles
Full title
Decrease in p3-Alcβ37 and p3-Alcβ40, products of Alcadein β generated by γ-secretase cleavages, in aged monkeys and patients with Alzheimer's disease
Authors, Artists and Contributors
Author / Creator
Omori, Chiori
Kimura, Ayano
Saito, Haruka
Kimura, Nobuyuki
Gupta, Veer
Pedrini, Steve
Hone, Eugene
Chatterjee, Pratishtha
Taddei, Kevin
Kasuga, Kensaku
Ikeuchi, Takeshi
Waragai, Masaaki
Nishimura, Masaki
Hu, Anqi
Nakaya, Tadashi
Meijer, Laurent
Maeda, Masahiro
Yamamoto, Tohru
Masters, Colin L.
Rowe, Chris C.
Ames, David
Yamamoto, Kazuo
Martins, Ralph N.
Gandy, Sam
Suzuki, Toshiharu
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6854065
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6854065
Other Identifiers
ISSN
2352-8737
E-ISSN
2352-8737
DOI
10.1016/j.trci.2019.09.015
