Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic over...
Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease
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Author / Creator
INVENT Consortium , Veterans Affairs’ Million Veteran Program , Klarin, Derek , Busenkell, Emma , Judy, Renae , Lynch, Julie , Levin, Michael , Haessler, Jeffery , Aragam, Krishna , Chaffin, Mark , Haas, Mary , Lindström, Sara , Assimes, Themistocles L. , Huang, Jie , Min Lee, Kyung , Shao, Qing , Huffman, Jennifer E. , Kabrhel, Christopher , Huang, Yunfeng , Sun, Yan V. , Vujkovic, Marijana , Saleheen, Danish , Miller, Donald R. , Reaven, Peter , DuVall, Scott , Boden, William E. , Pyarajan, Saiju , Reiner, Alex P. , Trégouët, David-Alexandre , Henke, Peter , Kooperberg, Charles , Gaziano, J. Michael , Concato, John , Rader, Daniel J. , Cho, Kelly , Chang, Kyong-Mi , Wilson, Peter W. F. , Smith, Nicholas L. , O’Donnell, Christopher J. , Tsao, Philip S. , Kathiresan, Sekar , Obi, Andrea , Damrauer, Scott M. and Natarajan, Pradeep
Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Venous thromboembolism is a significant cause of mortality
1
, yet its genetic determinants are incompletely defined. We performed a discovery genome-wide association study in the Million Veteran Program and UK Biobank, with testing of approximately 13 million DNA sequence variants for association with venous thromboembolism (26,066 cases and...
Alternative Titles
Full title
Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease
Authors, Artists and Contributors
Author / Creator
Veterans Affairs’ Million Veteran Program
Klarin, Derek
Busenkell, Emma
Judy, Renae
Lynch, Julie
Levin, Michael
Haessler, Jeffery
Aragam, Krishna
Chaffin, Mark
Haas, Mary
Lindström, Sara
Assimes, Themistocles L.
Huang, Jie
Min Lee, Kyung
Shao, Qing
Huffman, Jennifer E.
Kabrhel, Christopher
Huang, Yunfeng
Sun, Yan V.
Vujkovic, Marijana
Saleheen, Danish
Miller, Donald R.
Reaven, Peter
DuVall, Scott
Boden, William E.
Pyarajan, Saiju
Reiner, Alex P.
Trégouët, David-Alexandre
Henke, Peter
Kooperberg, Charles
Gaziano, J. Michael
Concato, John
Rader, Daniel J.
Cho, Kelly
Chang, Kyong-Mi
Wilson, Peter W. F.
Smith, Nicholas L.
O’Donnell, Christopher J.
Tsao, Philip S.
Kathiresan, Sekar
Obi, Andrea
Damrauer, Scott M.
Natarajan, Pradeep
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6858581
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6858581
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/s41588-019-0519-3