Integrative analysis of pooled CRISPR genetic screens using MAGeCKFlute
Integrative analysis of pooled CRISPR genetic screens using MAGeCKFlute
About this item
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Author / Creator
Wang, Binbin , Wang, Mei , Zhang, Wubing , Xiao, Tengfei , Chen, Chen-Hao , Wu, Alexander , Wu, Feizhen , Traugh, Nicole , Wang, Xiaoqing , Li, Ziyi , Mei, Shenglin , Cui, Yingbo , Shi, Sailing , Lipp, Jesse Jonathan , Hinterndorfer, Matthias , Zuber, Johannes , Brown, Myles , Li, Wei and Liu, X. Shirley
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Genome-wide screening using CRISPR coupled with nuclease Cas9 (CRISPR–Cas9) is a powerful technology for the systematic evaluation of gene function. Statistically principled analysis is needed for the accurate identification of gene hits and associated pathways. Here, we describe how to perform computational analysis of CRISPR screens using the MAG...
Alternative Titles
Full title
Integrative analysis of pooled CRISPR genetic screens using MAGeCKFlute
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6862721
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6862721
Other Identifiers
ISSN
1754-2189
E-ISSN
1750-2799
DOI
10.1038/s41596-018-0113-7
