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Single-cell transcriptomic analysis of Alzheimer’s disease

Single-cell transcriptomic analysis of Alzheimer’s disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6865822

Single-cell transcriptomic analysis of Alzheimer’s disease

About this item

Full title

Single-cell transcriptomic analysis of Alzheimer’s disease

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2019-06, Vol.570 (7761), p.332-337

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Alzheimer’s disease is a pervasive neurodegenerative disorder, the molecular complexity of which remains poorly understood. Here, we analysed 80,660 single-nucleus transcriptomes from the prefrontal cortex of 48 individuals with varying degrees of Alzheimer’s disease pathology. Across six major brain cell types, we identified transcriptionally dist...

Alternative Titles

Full title

Single-cell transcriptomic analysis of Alzheimer’s disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6865822

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6865822

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-019-1195-2

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