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A CRISPR–Cas9 gene drive targeting doublesex causes complete population suppression in caged Anophel...

A CRISPR–Cas9 gene drive targeting doublesex causes complete population suppression in caged Anophel...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6871539

A CRISPR–Cas9 gene drive targeting doublesex causes complete population suppression in caged Anopheles gambiae mosquitoes

About this item

Full title

A CRISPR–Cas9 gene drive targeting doublesex causes complete population suppression in caged Anopheles gambiae mosquitoes

Publisher

New York: Nature Publishing Group US

Journal title

Nature biotechnology, 2018-12, Vol.36 (11), p.1062-1066

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Complete population collapse of malaria vector
Anopheles gambiae
in cages is achieved using a gene drive that targets
doublesex
.
In the human malaria vector
Anopheles gambiae
, the gene
doublesex
(
Agdsx
) encodes two alternatively spliced transcripts,
dsx-female
(
AgdsxF
) and
dsx-male
(
Agdsx...

Alternative Titles

Full title

A CRISPR–Cas9 gene drive targeting doublesex causes complete population suppression in caged Anopheles gambiae mosquitoes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6871539

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6871539

Other Identifiers

ISSN

1087-0156

E-ISSN

1546-1696

DOI

10.1038/nbt.4245

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