The γδ T cell receptor combines innate with adaptive immunity by utilizing spatially distinct region...
The γδ T cell receptor combines innate with adaptive immunity by utilizing spatially distinct regions for agonist-selection and antigen responsiveness
About this item
Full title
Author / Creator
Melandri, Daisy , Zlatareva, Iva , Chaleil, Raphaël A.G. , Dart, Robin J. , Chancellor, Andrew , Nussbaumer, Oliver , Polyakova, Oxana , Roberts, Natalie A. , Wesch, Daniela , Kabelitz, Dieter , Irving, Peter M. , John, Susan , Mansour, Salah , Bates, Paul A. , Vantourout, Pierre and Hayday, Adrian C.
Journal title
Language
English
Formats
More information
Scope and Contents
Contents
T cell receptor (TCR) γδ-expressing T lymphocytes compose evolutionarily conserved cells with paradoxical features. On the one hand, clonally expanded γδ T cells with unique specificities typify adaptive immunity. Conversely, large TCRγδ
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intraepithelial lymphocyte (γδ IEL) compartments exhibit limited TCR diversity and effect rapid, innate-...
Alternative Titles
Full title
The γδ T cell receptor combines innate with adaptive immunity by utilizing spatially distinct regions for agonist-selection and antigen responsiveness
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6874498
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6874498
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-018-0253-5
