FGF Signalling in the Self-Renewal of Colon Cancer Organoids
FGF Signalling in the Self-Renewal of Colon Cancer Organoids
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The progression of colorectal cancer (CRC) is supposedly driven by cancer stem cells (CSC) which are able to self-renew and simultaneously fuel bulk tumour mass with highly proliferative and differentiated tumour cells. However, the CSC-phenotype in CRC is unstable and dependent on environmental cues. Fibroblast growth factor 2 (FGF2) is essential...
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Full title
FGF Signalling in the Self-Renewal of Colon Cancer Organoids
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6874569
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6874569
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-53907-7