Germline and somatic mutations of homologous recombination-associated genes in Japanese ovarian canc...
Germline and somatic mutations of homologous recombination-associated genes in Japanese ovarian cancer patients
About this item
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Author / Creator
Sugino, Kentaro , Tamura, Ryo , Nakaoka, Hirofumi , Yachida, Nozomi , Yamaguchi, Manako , Mori, Yutaro , Yamawaki, Kaoru , Suda, Kazuaki , Ishiguro, Tatsuya , Adachi, Sosuke , Isobe, Masanori , Yamaguchi, Masayuki , Kashima, Katsunori , Motoyama, Teiichi , Inoue, Ituro , Yoshihara, Kosuke and Enomoto, Takayuki
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
We explored the frequency of germline and somatic mutations in homologous recombination (HR)-associated genes in major histological types of ovarian cancer. We performed targeted sequencing to assess germline and somatic mutations of 16 HR-associated genes and 4 mismatch repair (MMR) genes among 207 ovarian cancer patients (50 high-grade serous car...
Alternative Titles
Full title
Germline and somatic mutations of homologous recombination-associated genes in Japanese ovarian cancer patients
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6882827
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6882827
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-54116-y
