Rod bipolar cells dysfunction occurs before ganglion cells loss in excitotoxin-damaged mouse retina
Rod bipolar cells dysfunction occurs before ganglion cells loss in excitotoxin-damaged mouse retina
About this item
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Author / Creator
Shen, Yumeng , Luo, Xue , Liu, Shiliang , Shen, Ying , Nawy, Scott and Shen, Yin
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Progressive degeneration of retinal ganglion cells (RGCs) will cause a blinding disease. Most of the study is focusing on the RGCs itself. In this study, we demonstrate a decline of the presynaptic rod bipolar cells (RBCs) response precedes RGCs loss and a decrease of protein kinase Cα (PKCα) protein expression in RBCs dendrites, using whole-cell v...
Alternative Titles
Full title
Rod bipolar cells dysfunction occurs before ganglion cells loss in excitotoxin-damaged mouse retina
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6885518
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6885518
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-019-2140-x
