Multicenter, randomised, open-label, non-comparative phase 2 trial on the efficacy and safety of the...
Multicenter, randomised, open-label, non-comparative phase 2 trial on the efficacy and safety of the combination of bevacizumab and trabectedin with or without carboplatin in women with partially platinum-sensitive recurrent ovarian cancer
About this item
Full title
Author / Creator
Colombo, Nicoletta , Zaccarelli, Eleonora , Baldoni, Alessandra , Frezzini, Simona , Scambia, Giovanni , Palluzzi, Eleonora , Tognon, Germana , Lissoni, Andrea A. , Rubino, Daniela , Ferrero, Annamaria , Farina, Gabriella , Negri, Emanuele , Pesenti Gritti, Angela , Galli, Francesca , Biagioli, Elena , Rulli, Eliana , Poli, Davide , Gerardi, Chiara , Torri, Valter , Fossati, Roldano and D‘Incalci, Maurizio
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Background
Trabectedin, in addition to its antiproliferative effect, can modify the tumour microenvironment and this could be synergistic with bevacizumab. The efficacy and safety of trabectedin and bevacizumab ± carboplatin have never been investigated.
Methods
In this phase 2 study, women progressing between 6 and 12 months since their l...
Alternative Titles
Full title
Multicenter, randomised, open-label, non-comparative phase 2 trial on the efficacy and safety of the combination of bevacizumab and trabectedin with or without carboplatin in women with partially platinum-sensitive recurrent ovarian cancer
Authors, Artists and Contributors
Author / Creator
Zaccarelli, Eleonora
Baldoni, Alessandra
Frezzini, Simona
Scambia, Giovanni
Palluzzi, Eleonora
Tognon, Germana
Lissoni, Andrea A.
Rubino, Daniela
Ferrero, Annamaria
Farina, Gabriella
Negri, Emanuele
Pesenti Gritti, Angela
Galli, Francesca
Biagioli, Elena
Rulli, Eliana
Poli, Davide
Gerardi, Chiara
Torri, Valter
Fossati, Roldano
D‘Incalci, Maurizio
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6888836
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6888836
Other Identifiers
ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/s41416-019-0584-5
