Increased BBB permeability contributes to EGCG-caused cognitive function improvement in natural agin...
Increased BBB permeability contributes to EGCG-caused cognitive function improvement in natural aging rats: pharmacokinetic and distribution analyses
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Publisher
Singapore: Springer Singapore
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Language
English
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Singapore: Springer Singapore
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Previous studies report that (−)-epigallocatechin-3-gallate (EGCG), the most abundant polyphenolic ingredient in green tea, has high efficacy against Alzheimer’s disease (AD) in various in vivo and in vitro models. However, as a water-soluble component, how EGCG exerts its anti-AD effects in the brain was not elucidated. In the present study, we in...
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Increased BBB permeability contributes to EGCG-caused cognitive function improvement in natural aging rats: pharmacokinetic and distribution analyses
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6888860
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6888860
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ISSN
1671-4083
E-ISSN
1745-7254
DOI
10.1038/s41401-019-0243-7
