Enzymatic Characterization of Wild-Type and Mutant Janus Kinase 1
Enzymatic Characterization of Wild-Type and Mutant Janus Kinase 1
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Janus kinases (JAKs) are found constitutively associated with cytokine receptors and are present in an inactive state prior to cytokine exposure. Activating mutations of JAKs are causative for a number of leukemias, lymphomas, and myeloproliferative diseases. In particular, the JAK2
mutant is found in most human cases of polycythemia vera, a dis...
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Full title
Enzymatic Characterization of Wild-Type and Mutant Janus Kinase 1
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6896158
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6896158
Other Identifiers
ISSN
2072-6694
E-ISSN
2072-6694
DOI
10.3390/cancers11111701
