Inhibition of PRMT5 Attenuates Oxidative Stress-Induced Pyroptosis via Activation of the Nrf2/HO-1 S...
Inhibition of PRMT5 Attenuates Oxidative Stress-Induced Pyroptosis via Activation of the Nrf2/HO-1 Signal Pathway in a Mouse Model of Renal Ischemia-Reperfusion Injury
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Author / Creator
Wang, Lei , Liu, Xiuheng , Yang, Yuanyuan , Liu, Hao , Qiu, Tao , Chen, Zhiyuan , Diao, Changhui and Wu, Junfeng
Publisher
Cairo, Egypt: Hindawi Publishing Corporation
Journal title
Language
English
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Publication information
Publisher
Cairo, Egypt: Hindawi Publishing Corporation
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Contents
Background. Extensive evidence has demonstrated that oxidative stress, pyroptosis, and proinflammatory programmed cell death are related to renal ischemia/reperfusion (I/R) injury. However, the underlying mechanism remains to be illustrated. Protein arginine methylation transferase 5 (PRMT5), which mediates arginine methylation involved in the regu...
Alternative Titles
Full title
Inhibition of PRMT5 Attenuates Oxidative Stress-Induced Pyroptosis via Activation of the Nrf2/HO-1 Signal Pathway in a Mouse Model of Renal Ischemia-Reperfusion Injury
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6899313
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6899313
Other Identifiers
ISSN
1942-0900
E-ISSN
1942-0994
DOI
10.1155/2019/2345658
