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Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors

Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6919319

Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Most pancreatic neuroendocrine tumors (PNETs) do not produce excess hormones and are therefore considered ‘non-functional’
1

3
. As clinical behaviors vary widely and distant metastases are eventually lethal
2
,
4
, biological classifications might guide treatment. Using enhancer maps to infer gene regulatory programs, we...

Alternative Titles

Full title

Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6919319

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6919319

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/s41591-019-0493-4

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