Paeonol attenuates inflammation by targeting HMGB1 through upregulating miR-339-5p
Paeonol attenuates inflammation by targeting HMGB1 through upregulating miR-339-5p
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Author / Creator
Mei, Liyan , He, Meihong , Zhang, Chaoying , Miao, Jifei , Wen, Quan , Liu, Xia , Xu, Qin , Ye, Sen , Ye, Peng , Huang, Huina , Lin, Junli , Zhou, Xiaojing , Zhao, Kai , Chen, Dongfeng , Zhou, Jianhong , Li, Chun and Li, Hui
Publisher
London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
Sepsis is a life-threatening disease caused by infection. Inflammation is a key pathogenic process in sepsis. Paeonol, an active ingredient in moutan cortex (a Chinese herb), has many pharmacological activities, such as anti-inflammatory and antitumour actions. Previous studies have indicated that paeonol inhibits the expression of HMGB1 and the tr...
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Full title
Paeonol attenuates inflammation by targeting HMGB1 through upregulating miR-339-5p
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6920373
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6920373
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-55980-4
