AT1 and AT2 receptors modulate renal tubular cell necroptosis in angiotensin II-infused renal injury...
AT1 and AT2 receptors modulate renal tubular cell necroptosis in angiotensin II-infused renal injury mice
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Author / Creator
Zhu, Yongjun , Cui, Hongwang , Lv, Jie , Liang, Haiqin , Zheng, Yanping , Wang, Shanzhi , Wang, Min , Wang, Huanan and Ye, Feng
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Abnormal renin-angiotensin system (RAS) activation plays a critical role in the initiation and progression of chronic kidney disease (CKD) by directly mediating renal tubular cell apoptosis. Our previous study showed that necroptosis may play a more important role than apoptosis in mediating renal tubular cell loss in chronic renal injury rats, but...
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Full title
AT1 and AT2 receptors modulate renal tubular cell necroptosis in angiotensin II-infused renal injury mice
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6923374
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6923374
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-55550-8