Development of Adamantane-Conjugated TLR7/8 Agonists for Supramolecular Delivery and Cancer Immunoth...
Development of Adamantane-Conjugated TLR7/8 Agonists for Supramolecular Delivery and Cancer Immunotherapy
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Publisher
Australia: Ivyspring International Publisher Pty Ltd
Journal title
Language
English
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Publisher
Australia: Ivyspring International Publisher Pty Ltd
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Contents
Tumor-associated macrophages (TAMs) are often abundant in solid cancers, assuming an immunosuppressive (M2-like) phenotype which supports tumor growth and immune escape. Recent methods have focused on identification of means (e.g., drugs, nanomaterials) that polarize TAMs to a tumor suppressive (M1-like) phenotype; however, reducing the systemic si...
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Full title
Development of Adamantane-Conjugated TLR7/8 Agonists for Supramolecular Delivery and Cancer Immunotherapy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6924259
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6924259
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ISSN
1838-7640
E-ISSN
1838-7640
DOI
10.7150/thno.35434