Muc5ac null mice are predisposed to spontaneous gastric antro-pyloric hyperplasia and adenomas coupl...
Muc5ac null mice are predisposed to spontaneous gastric antro-pyloric hyperplasia and adenomas coupled with attenuated H. pylori-induced corpus mucous metaplasia
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United States: Nature Publishing Group
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English
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United States: Nature Publishing Group
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Gastric cancer (GC) is the third leading cause of cancer-related deaths worldwide and is strongly associated with chronic Helicobacter pylori (Hp) infection. The ability of Hp to closely adhere to the gastric surface protective mucous layer containing mucins (MUC in humans and Muc in animals), primarily Muc5ac, is integral in the stepwise pathogene...
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Muc5ac null mice are predisposed to spontaneous gastric antro-pyloric hyperplasia and adenomas coupled with attenuated H. pylori-induced corpus mucous metaplasia
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6927550
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6927550
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ISSN
0023-6837
E-ISSN
1530-0307
DOI
10.1038/s41374-019-0293-y