Human Cytomegalovirus Enhances Placental Susceptibility and Replication of Human Immunodeficiency Vi...
Human Cytomegalovirus Enhances Placental Susceptibility and Replication of Human Immunodeficiency Virus Type 1 (HIV-1), Which May Facilitate In Utero HIV-1 Transmission
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United States: Oxford University Press
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Language
English
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Publisher
United States: Oxford University Press
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Contents
Co-pathogens that threaten the fetus during gestation, including human cytomegalovirus (HCMV), may contribute to mother-to-child transmission of HIV-1. We show that HCMV infection of placental macrophages may promote HIV replication and transmission as a consequence of inflammation and inhibition of intrinsic antiviral responses.
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Full title
Human Cytomegalovirus Enhances Placental Susceptibility and Replication of Human Immunodeficiency Virus Type 1 (HIV-1), Which May Facilitate In Utero HIV-1 Transmission
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6927849
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6927849
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ISSN
0022-1899,1537-6613
E-ISSN
1537-6613
DOI
10.1093/infdis/jiy327