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Human Cytomegalovirus Enhances Placental Susceptibility and Replication of Human Immunodeficiency Vi...

Human Cytomegalovirus Enhances Placental Susceptibility and Replication of Human Immunodeficiency Vi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6927849

Human Cytomegalovirus Enhances Placental Susceptibility and Replication of Human Immunodeficiency Virus Type 1 (HIV-1), Which May Facilitate In Utero HIV-1 Transmission

About this item

Full title

Human Cytomegalovirus Enhances Placental Susceptibility and Replication of Human Immunodeficiency Virus Type 1 (HIV-1), Which May Facilitate In Utero HIV-1 Transmission

Publisher

United States: Oxford University Press

Journal title

The Journal of infectious diseases, 2018-09, Vol.218 (9), p.1464-1473

Language

English

Formats

Publication information

Publisher

United States: Oxford University Press

More information

Scope and Contents

Contents

Co-pathogens that threaten the fetus during gestation, including human cytomegalovirus (HCMV), may contribute to mother-to-child transmission of HIV-1. We show that HCMV infection of placental macrophages may promote HIV replication and transmission as a consequence of inflammation and inhibition of intrinsic antiviral responses.

Alternative Titles

Full title

Human Cytomegalovirus Enhances Placental Susceptibility and Replication of Human Immunodeficiency Virus Type 1 (HIV-1), Which May Facilitate In Utero HIV-1 Transmission

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6927849

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6927849

Other Identifiers

ISSN

0022-1899,1537-6613

E-ISSN

1537-6613

DOI

10.1093/infdis/jiy327

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