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Role of VEGFR‐1 in melanoma acquired resistance to the BRAF inhibitor vemurafenib

Role of VEGFR‐1 in melanoma acquired resistance to the BRAF inhibitor vemurafenib

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6933379

Role of VEGFR‐1 in melanoma acquired resistance to the BRAF inhibitor vemurafenib

About this item

Full title

Role of VEGFR‐1 in melanoma acquired resistance to the BRAF inhibitor vemurafenib

Publisher

England: John Wiley & Sons, Inc

Journal title

Journal of cellular and molecular medicine, 2020-01, Vol.24 (1), p.465-475

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

The vascular endothelial growth factor receptor‐1 (VEGFR‐1) is a tyrosine kinase receptor frequently expressed in melanoma. Its activation by VEGF‐A or placental growth factor (PlGF) promotes tumour cell survival, migration and invasiveness. Moreover, VEGFR‐1 stimulation contributes to pathological angiogenesis and induces recruitment of tumour‐ass...

Alternative Titles

Full title

Role of VEGFR‐1 in melanoma acquired resistance to the BRAF inhibitor vemurafenib

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6933379

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6933379

Other Identifiers

ISSN

1582-1838

E-ISSN

1582-4934

DOI

10.1111/jcmm.14755

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