Human β-defensin-3 reduces excessive autophagy in intestinal epithelial cells and in experimental ne...
Human β-defensin-3 reduces excessive autophagy in intestinal epithelial cells and in experimental necrotizing enterocolitis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Necrotizing enterocolitis (NEC) is a leading cause of mortality in preterm newborns. Intestinal barrier dysfunction is one key event in NEC pathogenesis. Human β-defensin-3 (hBD3), one member of cationic host defence peptides, was reported to reduce the development of necrotizing enterocolitis in a neonatal rat model. And autophagy was induced in t...
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Human β-defensin-3 reduces excessive autophagy in intestinal epithelial cells and in experimental necrotizing enterocolitis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6934505
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6934505
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-56535-3
