Therapeutic effects of statins against lung adenocarcinoma via p53 mutant-mediated apoptosis
Therapeutic effects of statins against lung adenocarcinoma via p53 mutant-mediated apoptosis
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The
p53
gene is an important tumour suppressor gene. Mutant
p53
genes account for about half of all lung cancer cases. There is increasing evidence for the anti-tumour effects of statins via inhibition of the mevalonate pathway. We retrospectively investigated the correlation between statin use and lung cancer prognosis using the Taiwan...
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Full title
Therapeutic effects of statins against lung adenocarcinoma via p53 mutant-mediated apoptosis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6938497
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6938497
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-56532-6
