The translation of non-canonical open reading frames controls mucosal immunity
The translation of non-canonical open reading frames controls mucosal immunity
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Author / Creator
Jackson, Ruaidhrí , Kroehling, Lina , Khitun, Alexandra , Bailis, Will , Jarret, Abigail , York, Autumn G. , Khan, Omair M. , Brewer, J. Richard , Skadow, Mathias H. , Duizer, Coco , Harman, Christian C. D. , Chang, Lelina , Bielecki, Piotr , Solis, Angel G. , Steach, Holly R. , Slavoff, Sarah and Flavell, Richard A.
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The annotation of the mammalian protein-coding genome is incomplete. Arbitrary size restriction of open reading frames (ORFs) and the absolute requirement for a methionine codon as the sole initiator of translation have constrained the identification of potentially important transcripts with non-canonical protein-coding potential
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Alternative Titles
Full title
The translation of non-canonical open reading frames controls mucosal immunity
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6939389
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6939389
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-018-0794-7