Is population structure in the genetic biobank era irrelevant, a challenge, or an opportunity?
Is population structure in the genetic biobank era irrelevant, a challenge, or an opportunity?
About this item
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Author / Creator
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
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Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Scope and Contents
Contents
Replicable genetic association signals have consistently been found through genome-wide association studies in recent years. The recent dramatic expansion of study sizes improves power of estimation of effect sizes, genomic prediction, causal inference, and polygenic selection, but it simultaneously increases susceptibility of these methods to bias...
Alternative Titles
Full title
Is population structure in the genetic biobank era irrelevant, a challenge, or an opportunity?
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6942007
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6942007
Other Identifiers
ISSN
0340-6717,1432-1203
E-ISSN
1432-1203
DOI
10.1007/s00439-019-02014-8
