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Synthesis and Pharmacological Evaluation of Hybrids Targeting Opioid and Neurokinin Receptors

Synthesis and Pharmacological Evaluation of Hybrids Targeting Opioid and Neurokinin Receptors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6943619

Synthesis and Pharmacological Evaluation of Hybrids Targeting Opioid and Neurokinin Receptors

About this item

Full title

Synthesis and Pharmacological Evaluation of Hybrids Targeting Opioid and Neurokinin Receptors

Publisher

Switzerland: MDPI AG

Journal title

Molecules (Basel, Switzerland), 2019-12, Vol.24 (24), p.4460

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Morphine, which acts through opioid receptors, is one of the most efficient analgesics for the alleviation of severe pain. However, its usefulness is limited by serious side effects, including analgesic tolerance, constipation, and dependence liability. The growing awareness that multifunctional ligands which simultaneously activate two or more tar...

Alternative Titles

Full title

Synthesis and Pharmacological Evaluation of Hybrids Targeting Opioid and Neurokinin Receptors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6943619

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6943619

Other Identifiers

ISSN

1420-3049

E-ISSN

1420-3049

DOI

10.3390/molecules24244460

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