Synthesis and Pharmacological Evaluation of Hybrids Targeting Opioid and Neurokinin Receptors
Synthesis and Pharmacological Evaluation of Hybrids Targeting Opioid and Neurokinin Receptors
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Morphine, which acts through opioid receptors, is one of the most efficient analgesics for the alleviation of severe pain. However, its usefulness is limited by serious side effects, including analgesic tolerance, constipation, and dependence liability. The growing awareness that multifunctional ligands which simultaneously activate two or more tar...
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Full title
Synthesis and Pharmacological Evaluation of Hybrids Targeting Opioid and Neurokinin Receptors
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6943619
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6943619
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules24244460