Ramucirumab plus docetaxel versus placebo plus docetaxel in patients with locally advanced or metast...
Ramucirumab plus docetaxel versus placebo plus docetaxel in patients with locally advanced or metastatic urothelial carcinoma after platinum-based therapy (RANGE): overall survival and updated results of a randomised, double-blind, phase 3 trial
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RANGE study investigators , Petrylak, Daniel P, Prof , de Wit, Ronald, Prof , Chi, Kim N, Prof , Drakaki, Alexandra, MD , Sternberg, Cora N, Prof , Nishiyama, Hiroyuki, Prof , Castellano, Daniel, MD , Hussain, Syed A, Prof , Fléchon, Aude, MD , Bamias, Aristotelis, Prof , Yu, Evan Y, Prof , van der Heijden, Michiel S, PhD , Matsubara, Nobuaki, MD , Alekseev, Boris, Prof , Necchi, Andrea, MD , Géczi, Lajos, PhD , Ou, Yen-Chuan, Prof , Coskun, Hasan Senol, Prof , Su, Wen-Pin, Prof , Bedke, Jens, Prof , Gakis, Georgios, Prof , Percent, Ivor J, MD , Lee, Jae-Lyun, Prof , Tucci, Marcello, MD , Semenov, Andrey, PhD , Laestadius, Fredrik, MD , Peer, Avivit, MD , Tortora, Giampaolo, Prof , Safina, Sufia, MD , Garcia del Muro, Xavier, PhD , Rodriguez-Vida, Alejo, MD , Cicin, Irfan, Prof , Harputluoglu, Hakan, Prof , Tagawa, Scott T, MD , Vaishampayan, Ulka, Prof , Aragon-Ching, Jeanny B, MD , Hamid, Oday, PharmD , Liepa, Astra M, PharmD , Wijayawardana, Sameera, PhD , Russo, Francesca, MD , Walgren, Richard A, MD , Zimmermann, Annamaria H, MS , Hozak, Rebecca R, PhD , Bell-McGuinn, Katherine M, MD and Powles, Thomas, Prof
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England: Elsevier Ltd
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English
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Publisher
England: Elsevier Ltd
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SummaryBackgroundRamucirumab—an IgG1 vascular endothelial growth factor receptor 2 antagonist—plus docetaxel was previously reported to improve progression-free survival in platinum-refractory, advanced urothelial carcinoma. Here, we report the secondary endpoint of overall survival results for the RANGE trial. MethodsWe did a randomised, double-bl...
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Full title
Ramucirumab plus docetaxel versus placebo plus docetaxel in patients with locally advanced or metastatic urothelial carcinoma after platinum-based therapy (RANGE): overall survival and updated results of a randomised, double-blind, phase 3 trial
Authors, Artists and Contributors
Author / Creator
Petrylak, Daniel P, Prof
de Wit, Ronald, Prof
Chi, Kim N, Prof
Drakaki, Alexandra, MD
Sternberg, Cora N, Prof
Nishiyama, Hiroyuki, Prof
Castellano, Daniel, MD
Hussain, Syed A, Prof
Fléchon, Aude, MD
Bamias, Aristotelis, Prof
Yu, Evan Y, Prof
van der Heijden, Michiel S, PhD
Matsubara, Nobuaki, MD
Alekseev, Boris, Prof
Necchi, Andrea, MD
Géczi, Lajos, PhD
Ou, Yen-Chuan, Prof
Coskun, Hasan Senol, Prof
Su, Wen-Pin, Prof
Bedke, Jens, Prof
Gakis, Georgios, Prof
Percent, Ivor J, MD
Lee, Jae-Lyun, Prof
Tucci, Marcello, MD
Semenov, Andrey, PhD
Laestadius, Fredrik, MD
Peer, Avivit, MD
Tortora, Giampaolo, Prof
Safina, Sufia, MD
Garcia del Muro, Xavier, PhD
Rodriguez-Vida, Alejo, MD
Cicin, Irfan, Prof
Harputluoglu, Hakan, Prof
Tagawa, Scott T, MD
Vaishampayan, Ulka, Prof
Aragon-Ching, Jeanny B, MD
Hamid, Oday, PharmD
Liepa, Astra M, PharmD
Wijayawardana, Sameera, PhD
Russo, Francesca, MD
Walgren, Richard A, MD
Zimmermann, Annamaria H, MS
Hozak, Rebecca R, PhD
Bell-McGuinn, Katherine M, MD
Powles, Thomas, Prof
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6946880
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6946880
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(19)30668-0
