High frequency of shared clonotypes in human B cell receptor repertoires
High frequency of shared clonotypes in human B cell receptor repertoires
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The human genome contains approximately 20 thousand protein-coding genes
1
, but the size of the collection of antigen receptors of the adaptive immune system that is generated by the recombination of gene segments with non-templated junctional additions (on B cells) is unknown—although it is certainly orders of magnitude larger. It has not b...
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Full title
High frequency of shared clonotypes in human B cell receptor repertoires
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6949180
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6949180
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-019-0934-8
