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SHERLOCK: nucleic acid detection with CRISPR nucleases

SHERLOCK: nucleic acid detection with CRISPR nucleases

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6956564

SHERLOCK: nucleic acid detection with CRISPR nucleases

About this item

Full title

SHERLOCK: nucleic acid detection with CRISPR nucleases

Publisher

London: Nature Publishing Group UK

Journal title

Nature protocols, 2019-10, Vol.14 (10), p.2986-3012

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Rapid detection of nucleic acids is integral to applications in clinical diagnostics and biotechnology. We have recently established a CRISPR-based diagnostic platform that combines nucleic acid pre-amplification with CRISPR–Cas enzymology for specific recognition of desired DNA or RNA sequences. This platform, termed specific high-sensitivity enzy...

Alternative Titles

Full title

SHERLOCK: nucleic acid detection with CRISPR nucleases

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6956564

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6956564

Other Identifiers

ISSN

1754-2189

E-ISSN

1750-2799

DOI

10.1038/s41596-019-0210-2

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