DNA hypermethylation of sirtuin 1 (SIRT1) caused by betel quid chewing—a possible predictive biomark...
DNA hypermethylation of sirtuin 1 (SIRT1) caused by betel quid chewing—a possible predictive biomarker for malignant transformation
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Publisher
Germany: BioMed Central Ltd
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Language
English
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Publisher
Germany: BioMed Central Ltd
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Contents
DNA hypermethylation of tumor suppressor genes is observed in precancerous lesions and oral cancer of individuals with the habits of betel quid (BQ) chewing. SIRT1 has been identified as playing a role in the maintenance of epithelial integrity, and its alteration is often related to carcinogenesis. However, the methylation and transcription status...
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Full title
DNA hypermethylation of sirtuin 1 (SIRT1) caused by betel quid chewing—a possible predictive biomarker for malignant transformation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6958620
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6958620
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ISSN
1868-7075,1868-7083
E-ISSN
1868-7083,1868-7075
DOI
10.1186/s13148-019-0806-y
