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p53-Mediated Tumor Suppression: DNA-Damage Response and Alternative Mechanisms

p53-Mediated Tumor Suppression: DNA-Damage Response and Alternative Mechanisms

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6966539

p53-Mediated Tumor Suppression: DNA-Damage Response and Alternative Mechanisms

About this item

Full title

p53-Mediated Tumor Suppression: DNA-Damage Response and Alternative Mechanisms

Publisher

Switzerland: MDPI AG

Journal title

Cancers, 2019-12, Vol.11 (12), p.1983

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

The tumor suppressor p53 regulates different cellular pathways involved in cell survival, DNA repair, apoptosis, and senescence. However, according to an increasing number of studies, the p53-mediated canonical DNA damage response is dispensable for tumor suppression. p53 is involved in mechanisms regulating many other cellular processes, including...

Alternative Titles

Full title

p53-Mediated Tumor Suppression: DNA-Damage Response and Alternative Mechanisms

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6966539

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6966539

Other Identifiers

ISSN

2072-6694

E-ISSN

2072-6694

DOI

10.3390/cancers11121983

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