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Tanshinone IIA enhances the inhibitory effect of imatinib on proliferation and motility of acute leu...

Tanshinone IIA enhances the inhibitory effect of imatinib on proliferation and motility of acute leu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6967082

Tanshinone IIA enhances the inhibitory effect of imatinib on proliferation and motility of acute leukemia cell line TIB‑152 in vivo and in vitro by inhibiting the PI3K/AKT/mTOR signaling pathway

About this item

Full title

Tanshinone IIA enhances the inhibitory effect of imatinib on proliferation and motility of acute leukemia cell line TIB‑152 in vivo and in vitro by inhibiting the PI3K/AKT/mTOR signaling pathway

Author / Creator

Publisher

Greece: Spandidos Publications

Journal title

Oncology reports, 2020-02, Vol.43 (2), p.503-515

Language

English

Formats

Publication information

Publisher

Greece: Spandidos Publications

More information

Scope and Contents

Contents

Acute lymphoblastic leukemia (ALL) is a malignant hematological disease. Tanshinone IIA (Tan IIA) has antitumor activity in vitro and in vivo. The aim of the present study was to investigate the effects of Tan IIA in combination with imatinib (IM) on the proliferation, apoptosis, migration and invasion of acute T lymphocytic leukemia TIB‑152 cells...

Alternative Titles

Full title

Tanshinone IIA enhances the inhibitory effect of imatinib on proliferation and motility of acute leukemia cell line TIB‑152 in vivo and in vitro by inhibiting the PI3K/AKT/mTOR signaling pathway

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6967082

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6967082

Other Identifiers

ISSN

1021-335X

E-ISSN

1791-2431

DOI

10.3892/or.2019.7453

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