LRP-1 functionalized polymersomes enhance the efficacy of carnosine in experimental stroke
LRP-1 functionalized polymersomes enhance the efficacy of carnosine in experimental stroke
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Author / Creator
Kim, Eun-Sun , Kim, Donghyun , Nyberg, Sophie , Poma, Alessandro , Cecchin, Denis , Jain, Saurabh A. , Kim, Kyeong-A , Shin, Young-Jun , Kim, Eun-Hye , Kim, Minyeong , Baek, Seung-Hoon , Kim, Jin-Ki , Doeppner, Thorsten R. , Ali, Ali , Redgrave, Jessica , Battaglia, Giuseppe , Majid, Arshad and Bae, Ok-Nam
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Stroke is one of the commonest causes of death with limited treatment options. L-Carnosine has shown great promise as a neuroprotective agent in experimental stroke, but translation to the clinic is impeded by the large doses needed. We developed and evaluated the therapeutic potential of a novel delivery vehicle which encapsulated carnosine in lip...
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Full title
LRP-1 functionalized polymersomes enhance the efficacy of carnosine in experimental stroke
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6971073
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6971073
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-57685-5
