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Binding of myeloperoxidase to the extracellular matrix of smooth muscle cells and subsequent matrix...

Binding of myeloperoxidase to the extracellular matrix of smooth muscle cells and subsequent matrix...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6971288

Binding of myeloperoxidase to the extracellular matrix of smooth muscle cells and subsequent matrix modification

About this item

Full title

Binding of myeloperoxidase to the extracellular matrix of smooth muscle cells and subsequent matrix modification

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2020-01, Vol.10 (1), p.666, Article 666

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The extracellular matrix (ECM) of tissues is susceptible to modification by inflammation-associated oxidants. Considerable data support a role for hypochlorous acid (HOCl), generated by the leukocyte-derived heme-protein myeloperoxidase (MPO) in these changes. HOCl can modify isolated ECM proteins and cell-derived matrix, with this resulting in dec...

Alternative Titles

Full title

Binding of myeloperoxidase to the extracellular matrix of smooth muscle cells and subsequent matrix modification

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6971288

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6971288

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-019-57299-6

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