Ovarian mitochondrial dynamics and cell fate regulation in an androgen-induced rat model of polycyst...
Ovarian mitochondrial dynamics and cell fate regulation in an androgen-induced rat model of polycystic ovarian syndrome
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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In this study, we investigated in an androgenized rat model the involvement of autophagy and mitochondrial dynamics in granulosa cells in the pathogenesis of polycystic ovarian syndrome (PCOS) and its modulation by exogenous gonadotropin (eCG). We found 5α-dihydrotestosterone (DHT) treatment reduces ovarian length and weight with predominantly late...
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Full title
Ovarian mitochondrial dynamics and cell fate regulation in an androgen-induced rat model of polycystic ovarian syndrome
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6978404
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6978404
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-57672-w
