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T cell receptor gene therapy targeting WT1 prevents acute myeloid leukemia relapse post-transplant

T cell receptor gene therapy targeting WT1 prevents acute myeloid leukemia relapse post-transplant

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6982533

T cell receptor gene therapy targeting WT1 prevents acute myeloid leukemia relapse post-transplant

About this item

Full title

T cell receptor gene therapy targeting WT1 prevents acute myeloid leukemia relapse post-transplant

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2019-07, Vol.25 (7), p.1064-1072

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Relapse after allogeneic hematopoietic cell transplantation (HCT) is the leading cause of death in patients with acute myeloid leukemia (AML) entering HCT with poor-risk features
1

3
. When HCT does produce prolonged relapse-free survival, it commonly reflects graft-versus-leukemia effects mediated by donor T cells reactive with antig...

Alternative Titles

Full title

T cell receptor gene therapy targeting WT1 prevents acute myeloid leukemia relapse post-transplant

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6982533

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6982533

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/s41591-019-0472-9

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