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Mitochondrial dysfunctions trigger the calcium signaling-dependent fungal multidrug resistance

Mitochondrial dysfunctions trigger the calcium signaling-dependent fungal multidrug resistance

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6983421

Mitochondrial dysfunctions trigger the calcium signaling-dependent fungal multidrug resistance

About this item

Full title

Mitochondrial dysfunctions trigger the calcium signaling-dependent fungal multidrug resistance

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2020-01, Vol.117 (3), p.1711-1721

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Drug resistance in fungal pathogens has risen steadily over the past decades due to long-term azole therapy or triazole usage in agriculture. Modification of the drug target protein to prevent drug binding is a major recognized route to induce drug resistance. However, mechanisms for nondrug target-induced resistance remain only loosely defined. He...

Alternative Titles

Full title

Mitochondrial dysfunctions trigger the calcium signaling-dependent fungal multidrug resistance

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6983421

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6983421

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1911560116

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