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Down‐regulation of MTHFD2 inhibits NSCLC progression by suppressing cycle‐related genes

Down‐regulation of MTHFD2 inhibits NSCLC progression by suppressing cycle‐related genes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6991687

Down‐regulation of MTHFD2 inhibits NSCLC progression by suppressing cycle‐related genes

About this item

Full title

Down‐regulation of MTHFD2 inhibits NSCLC progression by suppressing cycle‐related genes

Publisher

England: John Wiley & Sons, Inc

Journal title

Journal of cellular and molecular medicine, 2020-01, Vol.24 (2), p.1568-1577

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) is a bifunctional enzyme located in the mitochondria. It has been reported to be overexpressed in several malignancies. However, the relationship between the expression of MTHFD2 and non‐small cell lung cancer (NSCLC) remains largely unknown. In this study, we found that MTHFD2 was significantly ov...

Alternative Titles

Full title

Down‐regulation of MTHFD2 inhibits NSCLC progression by suppressing cycle‐related genes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6991687

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6991687

Other Identifiers

ISSN

1582-1838

E-ISSN

1582-4934

DOI

10.1111/jcmm.14844

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