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Trop2 is a driver of metastatic prostate cancer with neuroendocrine phenotype via PARP1

Trop2 is a driver of metastatic prostate cancer with neuroendocrine phenotype via PARP1

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6994991

Trop2 is a driver of metastatic prostate cancer with neuroendocrine phenotype via PARP1

About this item

Full title

Trop2 is a driver of metastatic prostate cancer with neuroendocrine phenotype via PARP1

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2020-01, Vol.117 (4), p.2032-2042

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Resistance to androgen deprivation therapy, or castration-resistant prostate cancer (CRPC), is often accompanied by metastasis and is currently the ultimate cause of prostate cancer-associated deaths in men. Recently, secondary hormonal therapies have led to an increase of neuroendocrine prostate cancer (NEPC), a highly aggressive variant of CRPC....

Alternative Titles

Full title

Trop2 is a driver of metastatic prostate cancer with neuroendocrine phenotype via PARP1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6994991

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6994991

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1905384117

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