HO-1 drives autophagy as a mechanism of resistance against HER2-targeted therapies
HO-1 drives autophagy as a mechanism of resistance against HER2-targeted therapies
About this item
Full title
Author / Creator
Publisher
New York: Springer US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Springer US
Subjects
More information
Scope and Contents
Contents
Purpose
Targeted therapies have resulted in major advances in the treatment of HER2-positive breast cancers. Despite this, up to 70% of patients will develop resistance to treatment within 2 years and new strategies for targeting resistant disease are needed.
Methods
To identify potential resistance mechanisms, we used the mouse MMTV-NIC-P...
Alternative Titles
Full title
HO-1 drives autophagy as a mechanism of resistance against HER2-targeted therapies
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6997276
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6997276
Other Identifiers
ISSN
0167-6806
E-ISSN
1573-7217
DOI
10.1007/s10549-019-05489-1
