Clinical relevance of TP53 hotspot mutations in high-grade serous ovarian cancers
Clinical relevance of TP53 hotspot mutations in high-grade serous ovarian cancers
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Background
Mutation of
TP53
is the most frequent genetic alteration in high-grade serous ovarian cancer (HGSOC). The impact of hotspot mutations of
TP53
and protein levels on patient outcomes in HGSOC has not been fully elucidated.
Methods
The study population (
n
= 791) comprised of HGSOC samples with
TP53
mutatio...
Alternative Titles
Full title
Clinical relevance of TP53 hotspot mutations in high-grade serous ovarian cancers
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7000721
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7000721
Other Identifiers
ISSN
0007-0920,1532-1827
E-ISSN
1532-1827
DOI
10.1038/s41416-019-0654-8
