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Survival of the fittest: how myeloid-derived suppressor cells survive in the inhospitable tumor micr...

Survival of the fittest: how myeloid-derived suppressor cells survive in the inhospitable tumor micr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7004852

Survival of the fittest: how myeloid-derived suppressor cells survive in the inhospitable tumor microenvironment

About this item

Full title

Survival of the fittest: how myeloid-derived suppressor cells survive in the inhospitable tumor microenvironment

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Cancer Immunology, Immunotherapy, 2020-02, Vol.69 (2), p.215-221

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Myeloid-derived suppressor cells (MDSC) are present in most cancer patients where they are significant contributors to the immune suppressive tumor microenvironment (TME). The TME is a hostile locale due to deficiencies in oxygen (hypoxia) and nutrients, and the presence of reactive oxygen species (ROS). The survival of tumor cells within the TME i...

Alternative Titles

Full title

Survival of the fittest: how myeloid-derived suppressor cells survive in the inhospitable tumor microenvironment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7004852

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7004852

Other Identifiers

ISSN

0340-7004

E-ISSN

1432-0851

DOI

10.1007/s00262-019-02388-8

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