Active nuclear import of the deacetylase Sirtuin-2 is controlled by its C-terminus and importins
Active nuclear import of the deacetylase Sirtuin-2 is controlled by its C-terminus and importins
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The NAD-dependent deacetylase Sirtuin-2 (SIRT2) functions in diverse cellular processes including the cell cycle, metabolism, and has important roles in tumorigenesis and bacterial infection. SIRT2 predominantly resides in the cytoplasm but can also function in the nucleus. Consequently, SIRT2 localisation and its interacting partners may greatly i...
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Active nuclear import of the deacetylase Sirtuin-2 is controlled by its C-terminus and importins
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7010746
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7010746
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-58397-6
